Line name:Xla.npffr1.1tmEXRC

Synonyms: npffr, gpr147‐KO


Non-standard MTA required: No

Mutated gene: neuropeptide FF receptor 1, gene 1

Phenotype:F0 KO animals presented a reduction in lurp transcription in white adipose tissue concomitant with a reduction in adipose tissue macrophage content.

Type of mutation: Crispr-Cas9 mediated mutation

Source lab: EXRC

Species: X. laevis

Publication: Hassnain Waqas SF, Noble A, Hoang AC, et al. Adipose tissue macrophages develop from bone marrow-independent progenitors in Xenopus laevis and mouse. J Leukoc Biol. 2017;102(3):845-855.