#25 Elas:TRDN-GFP3 [Xla.Tg.(Rno.elas:DNthra-GFP;cryga:GFP)Brown]

Line name: Xla.Tg.(Rno.elas:DNthra-GFP;cryga:GFP)Brown

Synonyms: Elastase:DNthra-GFP, Elastase::TRDN-GFP3


EXRC line: #25

Non-standard MTA required: No

Transgene description: 205 bp rat elastase promoter driving dominant negative (TRDN) form of the TRα (thyroid hormone receptor α) fused to GFP. REMI

Phenotype: GFP expression in the pancreas (in the nucleus of the acinar cells of NF54 tadpoles). Exocrine pancreatic cells are resistant to thyroid hormone.

Source lab: Brown lab

Publication: Mukhi, S., Mao, J. and Brown, D. (2008) “Remodelling the exocrine pancreas at metamorphosis in Xenopus laevis.” PNAS 105, 8962-8967.

Species: X laevis

Background strain:



Colour morph:

Line information can also be found in Xenbase.