HSPCre-CMV:tdTomato (HSPCre13) (Xla.Tg(hsp70-CMV:tdTomato,eYFP)Ryff)

HSPCre-CMV:tdTomato (HSPCre13) (Xla.Tg(hsp70-CMV:tdTomato,eYFP)Ryff)

(EXRC Line #36)

Cre recombinase under the heat-shock promoter HSP70.

As this strain contains a linked CMV driven gene encoding the red fluorescent protein tdTomato, offspring with Cre recombinase can be easily identified. F1 animals of this strain crossed to the C5 reporter strain reveal ubiquitous induction of the EYFP reporter upon heat-shock.

http://www.addgene.org/Gerhart_Ryffel Accession ID: 30525.

Roose,M., et. al. (2009) “Heat-shock inducible Cre strains to study organogenesis in transgenic Xenopus laevis.” Trans Res. 18, 595-605.

Sauert,K., et. al. (2012) “Heat-shock mediated overexpression of HNF1 mutations has differential effects on gene expression in the Xenopus pronephric kidney.” PLoS. ONE, Vol7(3) e33522.

I Sce-I – Ryffel lab