#71 NIBB6(scat3) [Xla.Tg(CAG:SCAT3)Ueno]

Line name:  Xla.Tg(CAG:SCAT3)Ueno

Synonyms: NIBB6(scat3)


EXRC line: #71

NIBB6(scat3) g-F2

(EXRC Line #71)

Non-standard MTA required: No

Transgene description: CAG promoter driving expression of SCAT3

Phenotype: CAG promoter driving expression of SCAT3, the Caspase 3 activation (apoptosis) sensor and the rabbit β-globin polyA signal sequence. SCAT3 is a hybrid protein of seCFP-Venus linked with the caspase-3 recognition sequence (DEVD). Apoptosis is detected using FRET technology, the wavelength of emitted light changes when the the two fluorophores are no longer in close proximity. See (Takemoto et al. 2003 J. Cell Biol. 160, 235–243)


Source lab: Ueno lab

Publication: (Kominami et al. 2006 Genes Cells 11, 701–717).

Species: X. laevis

Background strain:



Colour morph: Pigmented

Line information can also be found in Xenbase.