Line name: Xla.Tg(WntREs:deGFP)1Vlemx
Synonyms: pbin7Lef:dGFP (pseudo-albino) (F2)
RRID: EXRC_0066
EXRC line: #66
Non-standard MTA required: No
Transgene description: A synthetic Wnt-responsive promoter – consisting of 7 copies of a TCF/LEF1 binding DNA element and a minimal TATA box driving destabilized EGFP and a polyA sequence. The transgene is flanked on both sides by two copies of the chicken HS4-core sequence. See Tran et al., 2010 and 2013 for a full description. REMI
Phenotype: GFP expression reveals dynamic patterns of Wnt/β-catenin signalling activity.
First clear signals present at neurula stage in the neural folds.
Source lab: Vleminckx lab
Publication: Hong Thi Tran, Kris Vleminckx, Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus,
Methods,Volume 66,2014,422-432
Species: X. laevis
Background strain:
Paternal:
Maternal:
Colour morph: pseudo albino
