Phenotype: Homozygous tailbud stage embryos (tbxt (t, Xbra) -/- tbxt.2 (t2,Xbra3) -/- ) do not develop any tail.
X. tropicalis mutant lines
Xtr.tbxttmJcsm Xbra talen mutant
Phenotype: The null mutation abrogates mesodermal cell determination at the very posterior end. Heterozygous line t (Xbra) -/+ does not show any overt phenotype. Homozygous t (Xbra) -/- tailbud shows slightly truncated tail.
Xtr.atp7amZimml kaleidoscope
Phenotype: Retinal epithelium pigmentation is variegated, melanocytes reduced, head cartilage defects. Model for Menkes disease.
Xtr.legmZimml legolas
Phenotype: Homozygous tadpoles display enlarged inner ear otoconia and vestibular defects.
Xtr.tupmZimml tailup
Phenotype: The end of the tail of homozygous 4-day-old tup tadpoles bend sharply upwards.
Xtr.dstmZimml desert tad
Phenotype: Homozygous embryos lack circulating blood cells and show reduced alpha globin expression. Heartbeat is normal.
#6016 Xtr.bunmZimml Bunny
Phenotype: homozygotes develop small dysmorphic otic vesicles with a single enlarged sensory macula and display vestibular defects.
Xtr.mammZimml marathon man
Phenotype: Homozygotes show very slow or absent heartbeat.
Xtr.askmZimml Airsick
Phenotype: Enlarged otoconia in inner ear; vestibular behavioural defect.
Xtr.smad4.1mZimml white hart
Phenotype: Homozygous mutants have little or no circulating blood cells. An unusual lump around the proctodeum is visible as early as ~stage 37, with subsequent ventral fin defects.
Xtr.myh6mZimml muzak
Phenotype: no heartbeat
Xtr.supt5hmZimml cyd vicious
Phenotype: Pleiotropic effect on eye (retinal lamination defect, no lens), neural crest (poor/absent melanophore migration).
Xtr.npntmZimml xenopus de milo
Phenotype: Homozygotes lack all forelimb structures, otherwise development appears normal. Green fluorescence in the heart. This is a serendipitous insertion of the nkx2-5:GFP transgene (Mohun lab) into intron 1 of the nephronectin gene. Homozygous transgenics show the xdm phenotype.
Xtr.unc45bmZimml Dicky Ticker (dit)
Phenotype: Homozygote mutants are completely paralysed and have no heartbeat due to disrupted striated muscle myofibrillogenesis.
Xtr.oc90mZimml komimi
Phenotype: Homozygous tadpoles display balance defects and inner ear defects in otoconial formation. At stage 45, kom tadpoles show a single enlarged otoconium located over each inner ear macula sensory epithelium.
